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12 Interaction with Carbapenem Antibiotics Carbapenem antibiotics (for example, ertapenem, imipenem, meropenem; this is depakote not a complete list) may reduce serum valproate concentrations to subtherapeutic levels, resulting in loss of seizure control .
Serum valproate topamax vs depakote is depakote a antipsychotic can you take depakote while pregnant depakote dosage concentrations should be monitored frequently after initiating carbapenem therapy .
Alternative antibacterial or anticonvulsant therapy should be considered if serum valproate concentrations drop significantly or seizure control deteriorates depakote [see Drug Interactions (7 .
13 Somnolence in the Elderly In a double-blind, multicenter trial depakote information depakote for nerve pain how depakote works depakote pcos depakote price how of valproate in elderly patients with dementia (mean age = 83 years), doses were increased by 125 mg/day to a target dose of 20 mg/kg/day .
A significantly higher proportion of valproate patients had somnolence compared to depakote for depression reviews depakote during pregnancy depakote attorney depakote dopamine what placebo, and although not statistically significant, there was a higher proportion of patients with dehydration .
Discontinuations depakote for somnolence were also significantly higher than with placebo .
In some patients with somnolence (approximately one-half), there was associated reduced depakote onset of action depakote 1000 mg is depakote a benzo depakote delayed release depakote er nutritional intake and weight loss .
There was a trend depakote for the patients who experienced these events to have a lower baseline albumin concentration, lower valproate clearance, and a higher BUN .
In elderly patients, depakote dosage should be increased more slowly and with regular monitoring for fluid and nutritional intake, dehydration, somnolence, and other adverse reactions .
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